Hi Jason,
This is purely my opinion and it’s based on the experience I have, but I would not suggest you to go that route.
I suggest you select the modular approach which allows you to build the city from building blocks. The modularity allows you to re-use same pieces multiple times in different places and situations. You can use the same geometry (e.g. piece of a wall) but different material (with a different texture) to create an illusion of a different type of a wall. You can create many different pieces that fit together and combine them ultimately allowing you to have a lot of variety. You can also create smaller assets like trash cans, lights, cars, vegetation etc. that you just reuse all over the city.
I would suggest you to go through the course and there’s later a section for creating game assets. This section takes the suggested approach how to create the assets for the games and game engines.
Cheers, Jax