I’m not 100% sure what you mean. Is it that you want an actor to move from point a to point b?if so, move the sequencer to the first key frame and then move the actor to the desired location. Then, move the sequencer to the second key frame and again move the actor.
This of course assumes you have added tve transform to the sequencer, a step required in newer versions (4.27 or later)
There is an explanation of this here: